Levamisole Anti-parasites. 30 Pills For People and Pets
Levamisole Anti-parasites. 30 Pills For People and Pets
Levamisol, brand names include: Ergamisol / Dicaris, also known as Levakolumbin, Tramisol, Avitrol, Harka Verm) is a medicine for the treatment of roundworms. This is the white roundworm that lives in the liver, brain, kidneys, lungs and intestines. With the recommended doses, it is practically without side effects. Single doses of 50 to 150 mg (2.5 mg per kilogram of body weight) will eliminate all parasites in 90 to 100% of patients with ascariasis regardless of worm burden. That's 6 pills for humans. It has been shown that anti-lever activity has not been determined for levamisole, but the most effective treatment regimen has not been determined. Additional drug studies are needed to better evaluate efficacy.
Levamisole has little or no curative action on pinworm and pinworm infections. It may have some activity against strongyloides, but confirmatory studies are needed. Levamisole has been shown to have significant activity against Wuchereria bancrofti and Brugia malayi microfilariae. It is not, however, as effective as diethylcarbamazine ("Hetrazan"), and the side effects are greater. In tolerated doses, levamisole has no significant actions on adult forms or microfilariae of Onchoceea volvulus. However, the topically applied drug may find a place in the treatment of ocular onchocerciasis. Limited studies with levamisole for toxoplasmosis and chronic cutaneous leishmaniasis have shown promising results and further studies are indicated.
An anthelmintic drug that has been tried experimentally in rheumatic conditions, where it appears to restore the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this improvement in immunity appears to be beneficial in rheumatoid arthritis where dermatitis has been reported , leukopenia and thrombocytopenia and nausea and vomiting as side effects. (From Smith and Reynard, Handbook of Pharmacology, 1991, p435-6). Levamisole was withdrawn from the US and Canadian markets in 2000, respectively, due to the risk of serious side effects and the availability of more effective substitute drugs. Levamisole refers to tetramysol Levo, it is the Levo isomer of tetramysol. It can selectively inhibit succinate dehydrogenase in the muscle of the parasite, so that it stops the reduction of succinic acid from fumaric acid. Therefore, the parasite's muscle metabolism lacks oxygen and leads to decreased energy.
The L-isomer is active against helmet with 1-2 times higher active efficiency and less toxic and side effects than tetramysol. It is a broad-spectrum anthelmintic with very good activity against roundworms, hookworms, tapeworms and strong sterilorals. It is an immunomodulator and has an effect on rheumatic disorders.
For the treatment of gastrointestinal and pulmonary nematodes in pigeons (Ascarida, Capillaria, Heterakis, Syngamus, Amidostomum), in dogs (Toxocara canis, Toxocara cati, Toxocaris leonina, Ancylostoma caninum, A. Braziliensis, A. tubaeformes, Uncinaro stenoides, Crenosoma vulpis, Angiostrongylus vasorum) and rabbits (Trichostrongylus spp., Trichocephalus spp., etc.) Levamisole hydrochloride 23 mg
For the treatment of gastrointestinal and pulmonary nematodes in pigeons, (Ascarida, Capillaria, Heterakis, Syngamus, Amidostomum), in dogs (Toxocara canis, Toxocara cati, Toxocaris leonina, Ancylostoma caninum, A. Braziliensis, A. tubaeformenoes, A. tubaeformenoes, A. tubaeformenoes, A. tubaeformenoes, A. tubaeforme Filaroides osleri, Crenosoma vulpis, Angiostrongylus vasorum) and rabbits (Trichostrongylus spp., Trichocephalus spp., Etc.) Levamisole hydrochloride 23 mg